EDUCATION
Post-Doctoral Research in Human Genetics, University of California Los Angeles (UCLA), USA
Ph.D. in Genetics, Indian Institute of Technology Kharagpur
M.Sc. in Genetics, University of Calcutta
B.Sc. (H) in Zoology, Scottish Church College, University of Calcutta
FELLOWSHIP AND AWARDS
Newton Bhabha PhD placement Fellowship (2018)
CSIR Junior Research Fellowship (JRF-NET) (2015)
Indian Academy of Science Summer Research Fellowship (2013)
RESEARCH INTEREST
Dr. Das’s research focuses on understanding how genetic and epigenetic factors contribute to complex traits and diseases such as cardiometabolic diseases. He utilizes multi-omics approaches to investigate gene regulatory mechanisms at single cell resolution.
PUBLICATIONS (SELECTED)
Das SS, Kar A, Rajkumar S, Lee SHT, Alvarez M, Pietiläinen KH, Pajukanta P. Cross-tissue single nucleus RNA sequencing discovers tissue-resident adipocytes involved in propanoate metabolism in the human heart. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023;43(10):1788-1804.
Garske K, Kar A, Comenho C, Baillu B, Pan D, Bhagat Y, Rosenberg G, Koka A, Das SS, Miao Z, Sinsheimer J, Kaprio J, Pietiläinen K, and Pajukanta P. Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes. Nature Communications. 2023;14(1):4214.
Kar A, Alvarez M, Garske KM, Huang H, Lee SHT, Deal M, Das SS, Koka A, Jamal Z, Mohlke KL, Laakso M, Heinonen S, Pietiläinen KH, Pajukanta P. Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions. Genome Medicine. 2024;16(1):19.
Darci-Maher N, Alvarez M, Arasu UT, Selvarajan I, Lee SHT, Pan DJ, Miao Z, Das SS, Kaminska D, Örd T, Benhammou JN, Wabitsch M, Pisegna JR, Männistö V, Pietiläinen KH, Laakso M, Sinsheimer JS, Kaikkonen MU, Pihlajamäki J, Pajukanta P. Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease. EBioMedicine. 2023;92:104620.
Das SS, Chakravorty N. Identification of deleterious SNPs and their effects on BCL11A, the master regulator of fetal hemoglobin expression. Genomics. 2020 Jan;112(1):397-403.
Das SS, Mitra A, Chakravorty N. Diseases and their clinical heterogeneity - Are we ignoring the SNiPers and micRomaNAgers? An illustration using Beta-thalassemia clinical spectrum and fetal hemoglobin levels. Genomics. 2019 Jan;111(1):67-75.
TEACHING AREA
- Human Genetics
- Genetic Engineering
- Bioinformatics